NGcGM3 (Bovine Spleen)
| Catalog Number | BL-M001147 |
| CAS Number | 2260670-78-6 |
| Description | NGcGM3 (Bovine Spleen), derived from bovine spleen tissue, is a formidable immunotherapeutic agent, leveraging its immunomodulatory properties in the fight against breast, lung, and colon cancer. In preclinical models, it has demonstrated remarkable efficacy in facilitating immune responses against the malignant cells and thus is considered a potential game-changer in the treatment of these dreaded diseases. In addition to its direct antitumor effects, NGcGM3 (Bovine Spleen) has shown promise as a vaccine adjuvant, elevating the potency and efficacy of cancer vaccines by providing additional augmentation to the body's immune response. |
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| IUPAC Name | ammonia;(2S,4S,5R,6R)-2-(((2S,3R,4S,5S,6R)-2-(((2R,3S,4R,5R,6R)-4,5-dihydroxy-6-(((2S,3R,E)-3-hydroxy-2-((Z)-tetracos-15-enamido)octadec-4-en-1-yl)oxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-4-hydroxy-5-(2-hydroxyacetamido)-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid |
| Synonyms | NGcGM3 Ganglioside (spleen); 15-Tetracosenamide, N-[(1S,2R,3E)-2-hydroxy-1-[[[O-[N-(2-hydroxyacetyl)-α-neuraminosyl]-(2→3)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]oxy]methyl]-3-heptadecen-1-yl]-, ammonium salt (1:1), (15Z)-; (15Z)-N-[(1S,2R,3E)-2-Hydroxy-1-[[[O-[N-(2-hydroxyacetyl)-α-neuraminosyl]-(2→3)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]oxy]methyl]-3-heptadecen-1-yl]-15-tetracosenamide ammonium salt |
| Molecular Weight | 1296.66 |
| Molecular Formula | C65H121N3O22 |
| Purity | >99% |
| Solubility | Soluble in Chloroform, Methanol |
| Appearance | White Solid |
| Shelf Life | 1 Year |
| Storage | Store at -20°C |
| Percent Composition | C 60.21% H 9.41% N 3.24% O 27.15% |
| Canonical SMILES | O=C(O)C1(OC2C(O)C(OC(CO)C2O)OC3C(O)C(O)C(OCC(NC(=O)CCCCCCCCCCCCCC=CCCCCCCCC)C(O)C=CCCCCCCCCCCCCC)OC3CO)OC(C(O)C(O)CO)C(NC(=O)CO)C(O)C1.N |
| InChI | InChI=1S/C65H118N2O22.H3N/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-51(75)66-45(46(72)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2)44-84-62-57(80)56(79)59(50(42-70)86-62)87-63-58(81)61(55(78)49(41-69)85-63)89-65(64(82)83)39-47(73)53(67-52(76)43-71)60(88-65)54(77)48(74)40-68;/h17-18,35,37,45-50,53-63,68-74,77-81H,3-16,19-34,36,38-44H2,1-2H3,(H,66,75)(H,67,76)(H,82,83);1H3/b18-17-,37-35+;/t45-,46+,47-,48+,49+,50+,53+,54+,55-,56+,57+,58+,59+,60+,61-,62+,63-,65-;/m0./s1 |
| InChI Key | REEGKSVAHNARFK-XHKMRSCRSA-N |
※ Please be kindly noted products are not for therapeutic use. We do not sell to patients.
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