ATP Liposomes

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BOC Sciences provide a series of ATP liposomes to meet your needs. The ATP concentration of a product has been determined using HPLC.

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Why Use ATP Liposomes?

The application/infusion of exogenous ATP appears to be an attractive possibility to restore the required ATP levels in ischemic cells. However, strongly charged anions (such as ATP) cannot penetrate the plasma membrane and enter the cell. In addition, ATP is rapidly degraded in the body, so its life span in the circulation is very short. These limitations do not allow free ATP to be used as a bioenergy substrate for therapy.
Encapsulating ATP in liposomes can prevent extracellular enzymatic hydrolysis, increase ATP circulation time, and enhance its intracellular permeability, which can significantly improve its effectiveness. BOC Sciences offers a series of ATP liposomes to facilitate drug delivery research. All liposomes are prepared under sterile conditions.

Technical Description



  1. Liang, W., Levchenko, T. S., & Torchilin, V. P. Encapsulation of ATP into liposomes by different methods: optimization of the procedure. Journal of Microencapsulation. 2004; 21(3):251-261.
  2. V Korb, K Tep, V Escriou, C Richard, D Scherman, L Cynober, J Chaumeil, G Dumortier. Current data on ATP-containing liposomes and potential prospects to enhance cellular energy status for hepatic applications. Crit Rev Ther Drug Carrier Syst. 2008; 25(4):305-45.
  3. D.D. Verma, T.S. Levchenko, E.A. Bernstein, and V.P. Torchilin. ATP-loaded Liposomes Effectively Protect Mechanical Functions of the Myocardium from Global Ischemia in an Isolated Rat Heart Model. J Control Release. 2005 Nov 28; 108(2-3):460-471.
  4. Dr. Ran Mo , Tianyue Jiang, Prof. Dr. Zhen Gu. Enhanced Anticancer Efficacy by ATP‐Mediated Liposomal Drug Delivery. Angewandte Chemie. 2014; 126(23):5925-5930.

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