Solution
- Liposomal Product Characterization
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Liposome Encapsulation
- Antigens Encapsulation
- Antioxidants Encapsulation
- Enzymes Encapsulation
- Liposomal Encapsulation Services: DNA
- Liposomal Encapsulation Services: Labeling Agents
- Liposomal Encapsulation Services: miRNA
- Liposomal Encapsulation Services: Oligonucleotide
- Liposomal Encapsulation Services: Proteins & Peptides
- Liposomal Encapsulation Services: siRNA
- Liposome Encapsulation Services: Drugs
- mRNA Encapsulation
- siRNA, miRNA, DNA, Proteins Encapsulation
- Vitamins & Minerals Encapsulation
- Formulation Solutions
- Custom Liposomes
- Process Development and Scale-up
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Online InquiryLiposomal Product Characterization
Online Inquiry
BOC Sciences characterizes liposome drugs according to the FDA production and control (CMC) guidelines. We can test for physicochemical properties, encapsulation efficiency, and in vitro drug release and stability, and other specifications.
Why Characterize Liposome Products?
Characterizing liposome products reinforce quality control, which can ensure reproducibility. Assessment of liposome critical quality attributes (CQAs), such as physicochemical properties, composition, encapsulation efficiency and drug release from liposome preparations, and establishing drug product specifications are all crucial for drug development.
Based on our comprehensive liposome platform, BOC Sciences uses a variety of technologies for liposome analysis to support drug development.
What Do We Do?
- Physicochemical Properties
- Determine particle size and polydispersity index (PDI)
- Zeta Potential
The particle size and distribution of liposomes are important parameters affecting drug loading, which determines the drug pharmacokinetics and pharmacodynamics in circulation and the stability of the liposome solution.
The measurement of liposome Zeta potential can provide insights into liposome stability, circulation time, protein interactions, granular cell permeability, and biocompatibility. By circumventing surface charge correlation, the biological properties of liposomes can be improved.
- Encapsulation Efficiency
- In Vitro Drug Release
- Stability Testing
- Product Specification
- Active Pharmaceutical Ingredients (APIs) Analysis
Encapsulation efficiency is one of the important parameters for assessing a drug delivery system. Drug encapsulation efficiency can be determine by the amount of drug contained in the liposome and comparing it with the total drug and liposome drug loading.
Liposomal drug release kinetics is a prerequisite for establishing a correlation between in vitro and in vivo studies of liposome drugs. Our team has adopted a series of analytical methods to better understand the drug release kinetics, such as the response to pH, temperature, the addition of excipients, changes in salt concentration.
Stability studies help overcome obstacles to the widespread use of liposomes. We determine liposome product stability under specific conditions.
We analyze of a range of parameters for liposome drug product specifications.
Drug ingredients are also key to liposomal drug products. The characteristics of API also contribute to the stability of liposome drugs.
BOC Sciences has extensive experience in supporting the characterization and management of liposome. In addition to our characterization service, we are happy to provide you with other products and services based on liposome technology. Please feel free to contact us for a detailed quote.
