VU0359595
| Catalog Number | BL-M000582 |
| CAS Number | 1246303-14-9 |
| Description | VU0359595 is an inhibitor of Phospholipase D1 (PLD1) (IC50 = 3.7 nM) exhibiting >1,700-fold selectivity for PLD1 over PLD2 (IC50 = 6.4 μM). It may function via interacting with an allosteric site of PLD. |
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| IUPAC Name | (1R,2R)-N-[(2S)-1-[4-(5-bromo-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]-2-phenylcyclopropane-1-carboxamide |
| Synonyms | CID-53361951; ML-270; (1R,2R)-N-([S]-1-{4-[5-bromo-2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxamide |
| Molecular Weight | 497.43 |
| Molecular Formula | C25H29BrN4O2 |
| Purity | ≥95% |
| Density | 1.395±0.06 g/cm3(Predicted) |
| Solubility | Soluble in DMSO (5 mg/ml) |
| Appearance | White to Beige Powder |
| Shelf Life | 1 Year |
| Storage | Store at -20°C |
| Percent Composition | C 60.36%, H 5.88%, Br 16.06%, N 11.26%, O 6.43% |
| Canonical SMILES | CC(CN1CCC(CC1)N2C3=C(C=C(C=C3)Br)NC2=O)NC(=O)C4CC4C5=CC=CC=C5 |
| InChI | InChI=1S/C25H29BrN4O2/c1-16(27-24(31)21-14-20(21)17-5-3-2-4-6-17)15-29-11-9-19(10-12-29)30-23-8-7-18(26)13-22(23)28-25(30)32/h2-8,13,16,19-21H,9-12,14-15H2,1H3,(H,27,31)(H,28,32)/t16-,20-,21+/m0/s1 |
| InChI Key | JSVNNLRZCJAYTQ-ORYQWCPZSA-N |
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