Ursodeoxycholic Acid
Ordering Information
| Catalog Number | Size | Price | Stock | Quantity |
|---|---|---|---|---|
| BL-M000467 | 100 g | $298 | In stock | |
| BL-M000467 | 1 kg | $949 | In stock |
| Catalog Number | BL-M000467 |
| CAS Number | 128-13-2 |
| Description | Ursodeoxycholic acid (UDCS) is a cell protectant used extensively to mitigate hepatic and biliary diseases. Ursodeoxycholic acid may be used to study its specific activities that range from reduction of cholesterol absorpition, cholesterol gallstone dissolution to suppression of immune response.IC50: M1-family aminopeptidase: IC50 = 2.6 µM (Plasmodium falciparum 3D7); NTCP: IC50 = 3.6 µM (human); HCT-116: IC50 = >50 µM (human); GBM: IC50 = >50 µM (human) Asbt: Ki= 75 µM (human) |
 | |
| IUPAC Name | (4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid |
| Synonyms | 5beta-cholanic acid-3alpha,7beta-diol; Actigall; ursodeoxycholate; ursodiol; Ursodeoxycholic acid |
| Molecular Weight | 392.57 |
| Molecular Formula | C24H40O4 |
| Boiling Point | 547.1°C |
| Melting Point | 203-204 °C (lit.) |
| Flash Point | 298.8°C |
| Purity | ≥ 99.0% |
| Density | 1.128 g/cm3 |
| Solubility | Soluble in Ethanol (50 mg/ml) |
| Appearance | White Crystal Powder |
| Application | Gallstone-dissolving drugs; Anti-neoplastic; For the prevention and treatment of cholesterol gallstones; Reduces hydrophobic bile acids and decreases both lymphocyte reactivity and serum alkaline phosphatase levels,IC50: M1-family aminopeptidase: IC50 = 2.6 µM (Plasmodium falciparum 3D7); NTCP: IC50 = 3.6 µM (human); HCT-116: IC50 = >50 µM (human); GBM: IC50 = >50 µM (human) Asbt: Ki= 75 µM (human) |
| Shelf Life | 1 Year |
| Storage | Store at RT |
| Percent Composition | C 73.43%, H 10.27%, O 16.30% |
| Canonical SMILES | CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C |
| InChI | 1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20+,22+,23+,24-/m1/s1 |
| InChI Key | RUDATBOHQWOJDD-UZVSRGJWSA-N |
※ Please be kindly noted products are not for therapeutic use. We do not sell to patients.
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