TMG-A13

Catalog NumberBL-M001264
CAS Number2247654-99-3
DescriptionThis glucoside can effectively stabilize a variety of membrane proteins including GPCRs. Due to its high tendency to form small protein-detergent complexes (PDCs), this is a promising tool for studying protein structures using X-ray crystallography and cryo-electron microscopy. This is a good alternative to OGNG because it significantly improves protein stabilization efficiency compared to OGNG.
IUPAC Name(2R,2'R,3S,3'S,4S,4'S,5R,5'R,6R,6'R)-6,6'-((2-(4,4-bis((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)heptadecyl)-2-tridecylpropane-1,3-diyl)bis(oxy))bis(2-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol)
SynonymsTandem malonate glucoside-A13; TMG-A 13
Molecular Weight1205.51
Molecular FormulaC59H112O24
Purity>99%
SolubilitySoluble in Chloroform, Methanol, Water
AppearanceWhite Solid
Shelf Life1 Year
StorageStore at -20 °C
Percent CompositionC 58.78%, H 9.36%, O 31.85%
Canonical SMILESOCC1OC(OCC(COC2OC(CO)C(O)C(O)C2O)(CCCCCCCCCCCCC)CCCC(COC3OC(CO)C(O)C(O)C3O)(COC4OC(CO)C(O)C(O)C4O)CCCCCCCCCCCCC)C(O)C(O)C1O
InChIInChI=1S/C59H112O24/c1-3-5-7-9-11-13-15-17-19-21-23-26-58(34-76-54-50(72)46(68)42(64)38(30-60)80-54,35-77-55-51(73)47(69)43(65)39(31-61)81-55)28-25-29-59(27-24-22-20-18-16-14-12-10-8-6-4-2,36-78-56-52(74)48(70)44(66)40(32-62)82-56)37-79-57-53(75)49(71)45(67)41(33-63)83-57/h38-57,60-75H,3-37H2,1-2H3/t38-,39-,40-,41-,42-,43-,44-,45-,46+,47+,48+,49+,50-,51-,52-,53-,54-,55-,56-,57-/m1/s1
InChI KeyKIHKGDGHLNBQJX-RPZVMPNISA-N

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