(R)-Edelfosine
| Catalog Number | BL-M000834 |
| CAS Number | 77286-66-9 |
| Description | (R)-Edelfosine is a synthetic lysophospholipid analogue that acts as an inhibitor of phosphatidylinositol phospholipase C (IC50 = 9.6 μM in fibroblasts and adenocarcinoma cells) and an agonist at platelet-activating factor (PAF) receptors. It induces apoptosis in human promyelocytic HL-60 leukemic cells and promonocytic U937 leukemic cells. |
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| IUPAC Name | [(2R)-2-methoxy-3-octadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate |
| Synonyms | 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide, (7R)-; 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide, (R)-; 1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphocholine; ET 18-OCH3; TLC ELL 12; (R)-2-methoxy-3-(octadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate; (7R)-4-Hydroxy-7-methoxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptacosan-1-aminium-4-oxide |
| Molecular Weight | 523.73 |
| Molecular Formula | C27H58NO6P |
| Purity | >99% |
| Solubility | Soluble in DMSO, Ethanol |
| Appearance | White Powder |
| Shelf Life | 1 Year |
| Storage | Store at -20°C |
| Percent Composition | C 61.92%, H 11.16%, N 2.67%, O 18.33%, P 5.91% |
| Canonical SMILES | CCCCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCC[N+](C)(C)C)OC |
| InChI | InChI=1S/C27H58NO6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-32-25-27(31-5)26-34-35(29,30)33-24-22-28(2,3)4/h27H,6-26H2,1-5H3/t27-/m1/s1 |
| InChI Key | MHFRGQHAERHWKZ-HHHXNRCGSA-N |
※ Please be kindly noted products are not for therapeutic use. We do not sell to patients.
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