PGF1α

Catalog NumberBL-M000668
CAS Number745-62-0
DescriptionPGF1α is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. This compound also acts as smooth muscle relaxant, however, PGF1α is only half as active as PGF2α (sc-201227) in inducing human respiratory smooth muscle contractions in vitro.
IUPAC Name7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]heptanoic acid
SynonymsProstaglandin F1α; PGF1alpha; PGF 1-alpha; 9α,11α,15S-trihydroxy-prost-13E-en-1-oic acid
Molecular Weight356.50
Molecular FormulaC20H36O5
Boiling Point526.6°C at 760 mmHg
Melting Point95-97°C
Purity>99%
Density1.1 g/cm3
SolubilitySoluble in ethanol (50 mg/ml), water (>2 mg/ml) at 25°C, PBS (pH 7.2) (2.1 mg/ml), DMSO (50 mg/ml), and DMF (50 mg/ml).
AppearancePowder
Shelf Life1 Year
StorageStore at -20°C
Percent CompositionC 67.38%, H 10.18%, O 22.44%
Canonical SMILESCCCCCC(C=CC1C(CC(C1CCCCCCC(=O)O)O)O)O
InChIInChI=1S/C20H36O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-19,21-23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,18-,19+/m0/s1
InChI KeyDZUXGQBLFALXCR-CDIPTNKSSA-N

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