N-Docosanoylsphingosine

Catalog NumberBL-M000958
CAS Number27888-44-4
DescriptionN-Docosanoylsphingosine is used in the treatment of lysosomal storage disorders such as Niemann-Pick disease. It acts as a pharmacological chaperone to promote proper folding and trafficking of defective enzymes, thus improving enzyme activity and reducing disease symptoms.
IUPAC NameN-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]docosanamide
SynonymsC22 Ceramide; N-(docosanoyl)-sphing-4-enine; Ceramide (d18:1/22:0); C22 Ceramide (d18:1/22:0)
Molecular Weight622.06
Molecular FormulaC40H79NO3
Boiling Point731.8±60.0 °C at 760 mmHg
Purity>99%
Density0.909±0.06 g/cm3
AppearancePowder
Shelf Life1 Year
StorageStore at -20°C
Percent CompositionC 77.23%, H 12.80%, N 2.25%, O 7.72%
Canonical SMILESCCCCCCCCCCCCCCCCCCCCCC(=O)NC(CO)C(C=CCCCCCCCCCCCCC)O
InChIInChI=1S/C40H79NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-24-26-28-30-32-34-36-40(44)41-38(37-42)39(43)35-33-31-29-27-25-23-16-14-12-10-8-6-4-2/h33,35,38-39,42-43H,3-32,34,36-37H2,1-2H3,(H,41,44)/b35-33+/t38-,39+/m0/s1
InChI KeyKEPQASGDXIEOIL-GLQCRSEXSA-N

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