N-Arachidonylglycine
| Catalog Number | BL-M000652 |
| CAS Number | 179113-91-8 |
| Description | N-Arachidonylglycine has been isolated from cell cultures treated with arachidonoyl ethanolamide. It is a GPR18 agonist with EC50 value of 44.5 nM. It is a kind of endogenous anandamide-like compound. It is also an endogenous GlyT2 inhibitor and acts as a glycine transporter inhibitor. It has also been synthesized as an analog of AEA for structure/activity testing. It may be produced endogenously via oxidation of AEA, or by transacylation of arachidonoyl CoA. It has analgesic activities in whole animal experiments. |
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| IUPAC Name | 2-[[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]amino]acetic acid |
| Synonyms | N-[1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl]-glycine; Arachidonyl Glycine; (all-Z)-N-(1-Oxo-5,8,11,14-eicosatetraenyl)glycine; N-[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraenyl]glycine |
| Molecular Weight | 361.52 |
| Molecular Formula | C22H35NO3 |
| Purity | ≥98% by HPLC |
| Appearance | Methylene Chloride |
| Shelf Life | 3 Months |
| Storage | Store at -20°C |
| Percent Composition | C 73.09%, H 9.76%, N 3.87%, O 13.28% |
| Canonical SMILES | CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCC(=O)O |
| InChI | InChI=1S/C22H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21(24)23-20-22(25)26/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-20H2,1H3,(H,23,24)(H,25,26)/b7-6-,10-9-,13-12-,16-15- |
| InChI Key | YLEARPUNMCCKMP-DOFZRALJSA-N |
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