Leukotriene A4 methyl ester

Catalog NumberBL-M000694
CAS Number73466-12-3
DescriptionLeukotriene A4 (LTA4) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA4 synthase activities. They are potent eicosanoid lipid mediators that play numerous roles in inflammation, immunological functions and maintaining biological homeostasis.
IUPAC Namemethyl 4-[(2S,3S)-3-[(1E,3E,5Z,8Z)-tetradeca-1,3,5,8-tetraenyl]oxiran-2-yl]butanoate
Synonyms2-Oxiranebutanoic acid, 3-(1E,3E,5Z,8Z)-1,3,5,8-tetradecatetraen-1-yl-, methyl ester, (2S,3S)-; Oxiranebutanoic acid, 3-(1,3,5,8-tetradecatetraenyl)-, methyl ester, [2S-[2α,3β(1E,3E,5Z,8Z)]]-; Oxiranebutanoic acid, 3-(1E,3E,5Z,8Z)-1,3,5,8-tetradecatetraenyl-, methyl ester, (2S,3S)-; (-)-LTA4 methyl ester; Leukotriene A methyl ester; LTA4 methyl ester
Molecular Weight332.48
Molecular FormulaC21H32O3
Boiling Point442.5±25.0°C at 760 mmHg
Purity>99%
Density0.997±0.06 g/cm3
SolubilitySoluble in Chloroform
AppearanceLiquid
Shelf Life1 Year
StorageStore at -20°C
Percent CompositionC 75.86%, H 9.70%, O 14.44%
Canonical SMILESCCCCCC=CCC=CC=CC=CC1C(O1)CCCC(=O)OC
InChIInChI=1S/C21H32O3/c1-3-4-5-6-7-8-9-10-11-12-13-14-16-19-20(24-19)17-15-18-21(22)23-2/h7-8,10-14,16,19-20H,3-6,9,15,17-18H2,1-2H3/b8-7-,11-10-,13-12+,16-14+/t19-,20-/m0/s1
InChI KeyWTKAVFHPLJFCMZ-NIBLXIPLSA-N

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