Leukotriene A4 methyl ester
| Catalog Number | BL-M000694 |
| CAS Number | 73466-12-3 |
| Description | Leukotriene A4 (LTA4) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA4 synthase activities. They are potent eicosanoid lipid mediators that play numerous roles in inflammation, immunological functions and maintaining biological homeostasis. |
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| IUPAC Name | methyl 4-[(2S,3S)-3-[(1E,3E,5Z,8Z)-tetradeca-1,3,5,8-tetraenyl]oxiran-2-yl]butanoate |
| Synonyms | 2-Oxiranebutanoic acid, 3-(1E,3E,5Z,8Z)-1,3,5,8-tetradecatetraen-1-yl-, methyl ester, (2S,3S)-; Oxiranebutanoic acid, 3-(1,3,5,8-tetradecatetraenyl)-, methyl ester, [2S-[2α,3β(1E,3E,5Z,8Z)]]-; Oxiranebutanoic acid, 3-(1E,3E,5Z,8Z)-1,3,5,8-tetradecatetraenyl-, methyl ester, (2S,3S)-; (-)-LTA4 methyl ester; Leukotriene A methyl ester; LTA4 methyl ester |
| Molecular Weight | 332.48 |
| Molecular Formula | C21H32O3 |
| Boiling Point | 442.5±25.0°C at 760 mmHg |
| Purity | >99% |
| Density | 0.997±0.06 g/cm3 |
| Solubility | Soluble in Chloroform |
| Appearance | Liquid |
| Shelf Life | 1 Year |
| Storage | Store at -20°C |
| Percent Composition | C 75.86%, H 9.70%, O 14.44% |
| Canonical SMILES | CCCCCC=CCC=CC=CC=CC1C(O1)CCCC(=O)OC |
| InChI | InChI=1S/C21H32O3/c1-3-4-5-6-7-8-9-10-11-12-13-14-16-19-20(24-19)17-15-18-21(22)23-2/h7-8,10-14,16,19-20H,3-6,9,15,17-18H2,1-2H3/b8-7-,11-10-,13-12+,16-14+/t19-,20-/m0/s1 |
| InChI Key | WTKAVFHPLJFCMZ-NIBLXIPLSA-N |
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