L-threo-sphingosine (d18:1)

Catalog NumberBL-M001090
CAS Number25695-95-8
DescriptionL-threo-Sphingosine (d18:1), an analog of D-erythro-sphingosine, inhibits protein kinase C in mixed micelle assays with 50% inhibition at 2.2 mol % making it a slightly more potent inhibitor compared to D-erythro-sphingosine (50% inhibition at 2.8 mol %) or other analogs of shorter alkyl chain length.
IUPAC Name(E,2S,3S)-2-aminooctadec-4-ene-1,3-diol
Synonyms(2S,3S,4E)-2-aminooctadec-4-ene-1,3-diol; 3-L-4-Sphingenine
Molecular Weight299.49
Molecular FormulaC18H37NO2
Boiling Point445.9±45.0 °C at 760 mmHg
Melting Point148.76°C
Purity>98%
Density0.9±0.1 g/cm3
SolubilitySoluble in ethanol (~0.25 mg/mL)
AppearanceCrystalline Solid
Shelf Life1 Year
StorageStore at -20°C
Percent CompositionC 72.19%, H 12.45%, N 4.68%, O 10.68%
Canonical SMILESCCCCCCCCCCCCCC=CC(C(CO)N)O
InChIInChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18-/m0/s1
InChI KeyWWUZIQQURGPMPG-DNWQSSKHSA-N

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