L-threo-sphingosine (d18:1)
Catalog Number | BL-M001090 |
CAS Number | 25695-95-8 |
Description | L-threo-Sphingosine (d18:1), an analog of D-erythro-sphingosine, inhibits protein kinase C in mixed micelle assays with 50% inhibition at 2.2 mol % making it a slightly more potent inhibitor compared to D-erythro-sphingosine (50% inhibition at 2.8 mol %) or other analogs of shorter alkyl chain length. |
IUPAC Name | (E,2S,3S)-2-aminooctadec-4-ene-1,3-diol |
Synonyms | (2S,3S,4E)-2-aminooctadec-4-ene-1,3-diol; 3-L-4-Sphingenine |
Molecular Weight | 299.49 |
Molecular Formula | C18H37NO2 |
Boiling Point | 445.9±45.0 °C at 760 mmHg |
Melting Point | 148.76°C |
Purity | >98% |
Density | 0.9±0.1 g/cm3 |
Solubility | Soluble in ethanol (~0.25 mg/mL) |
Appearance | Crystalline Solid |
Shelf Life | 1 Year |
Storage | Store at -20°C |
Percent Composition | C 72.19%, H 12.45%, N 4.68%, O 10.68% |
Canonical SMILES | CCCCCCCCCCCCCC=CC(C(CO)N)O |
InChI | InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18-/m0/s1 |
InChI Key | WWUZIQQURGPMPG-DNWQSSKHSA-N |
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