DSPE-PEG maleimide

Catalog NumberBL-M000001
CAS Number474922-22-0
DescriptionDSPE-PEG Maleimide is a functionalized PEG Lipid conjugate.
Synonyms1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)] ammonium salt; Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]-, ammonium salt
Molecular Formula(C2H4O)nC51H92N3O13P.H3N
Purity≥95%
SolubilitySoluble in chloroform and warm water.
AppearanceWhite solid powder.
ApplicationUsed in the preparation of neutral liposomes, immunoliposomes, and used to conjugate with P5 peptide to improve peptide incorporation into liposomes.
Shelf Life≥ 2 years.
StorageStore at -20°C, keep in dry and avoid sunlight.
ShippingShipped under RT.
DetailsDSPE-PEG(2000) Maleimide is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a maleimide, providing a thiol or cysteine reactive maleimide group during PEGylated liposome or micelle preparation.
PEG provides stealth property, extends circulation half-life, and reduces non-specific protein binding or cell adhesion. The reactive maleimide bioconjugates targeting molecules including antibody, aptamer, protein, and peptide.
Percent CompositionC 56.76%, H 9.29%, N 1.90%, O 31.00%, P 1.05%

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