DSPE-PEG Folate

Catalog NumberBL-M000010
CAS Number1236288-25-7
DescriptionDSPE-PEG-Folate is a conjugate of folic acid and amino-PEG-DSPE, used for folate-targeted PEGylated liposome preparation.
IUPAC Nameazane;5-[2-[2-[2-[2,3-di(octadecanoyloxy)propoxy-hydroxyphosphoryl]oxyethylcarbamoyloxy]ethoxy]ethylamino]-2-[[4-[(2-imino-4-oxo-4aH-pteridin-6-yl)methylamino]benzoyl]amino]-5-oxopentanoic acid
Synonyms1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000/5000] (ammonium salt)
Molecular Weight1319.6
Molecular Formula(C2H4O)nC63H104N9O15P
Purity≥95%
SolubilitySoluble in warm water; DMSO; DMF.
AppearanceYellow/orange solid.
ApplicationDSPE-PEG-Folate incorporated into liposomes serves as a targeting ligand. Folate targeted drug delivery is useful in diagnosing and treating cancer and inflammatory diseases.
Shelf Life1 Year
StorageStore at -20 ℃, protected from light and moisture.
ShippingAmbient Temperature.
Percent CompositionC 56.13%, H 8.92%, N 4.77%, O 29.22%, P 0.96%
Canonical SMILESCCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)OCCOCCNC(=O)CCC(C(=O)O)NC(=O)C1=CC=C(C=C1)NCC2=NC3C(=O)NC(=N)N=C3N=C2)OC(=O)CCCCCCCCCCCCCCCCC.N
InChIInChI=1S/C65H108N9O16P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-57(76)87-49-54(90-58(77)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)50-89-91(83,84)88-44-42-68-65(82)86-46-45-85-43-41-67-56(75)40-39-55(63(80)81)72-61(78)51-35-37-52(38-36-51)69-47-53-48-70-60-59(71-53)62(79)74-64(66)73-60;/h35-38,48,54-55,59,69H,3-34,39-47,49-50H2,1-2H3,(H,67,75)(H,68,82)(H,72,78)(H,80,81)(H,83,84)(H2,66,74,79);1H3

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