DSPE-PEG (2000) Maleimide
| Catalog Number | BL-M000001 |
| CAS Number | 474922-22-0 |
| Description | DSPE-PEG(2000) Maleimide is a functionalized PEG Lipid conjugate. |
 | |
| IUPAC Name | azanium;[(2R)-2,3-di(octadecanoyloxy)propyl] 2-[2-[(Z)-2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethenyl]peroxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyperoxyethoxycarbonylamino]ethyl phosphate;ethene |
| Synonyms | 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] (ammonium salt) |
| Molecular Weight | 2941.64 |
| Molecular Formula | C139H271N4O57P |
| Purity | ≥95% |
| Solubility | Soluble in chloroform and warm water. |
| Appearance | White solid powder. |
| Application | DSPE-PEG(2000) Maleimide has been used in the preparation of neutral liposomes, immunoliposomes, and used to conjugate with P5 peptide to improve peptide incorporation into liposomes. |
| Shelf Life | ≥ 2 years. |
| Storage | Store at -20°C, keep in dry and avoid sunlight. |
| Shipping | Shipped under RT. |
| Details | DSPE-PEG(2000) Maleimide is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a maleimide, providing a thiol or cysteine reactive maleimide group during PEGylated liposome or micelle preparation. PEG provides stealth property, extends circulation half-life, and reduces non-specific protein binding or cell adhesion. The reactive maleimide bioconjugates targeting molecules including antibody, aptamer, protein, and peptide. |
| Percent Composition | C 56.76%, H 9.29%, N 1.90%, O 31.00%, P 1.05% |
| Canonical SMILES | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCCNC(=O)OCCOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOC=CNC(=O)CCN1C(=O)C=CC1=O)OC(=O)CCCCCCCCCCCCCCCCC.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.[NH4+] |
| InChI | InChI=1S/C53H94N3O57P.43C2H4.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-51(60)66-45-47(71-52(61)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)46-70-114(63,64)69-42-39-55-53(62)65-43-44-68-73-75-77-79-81-83-85-87-89-91-93-95-97-99-101-103-105-107-109-111-113-112-110-108-106-104-102-100-98-96-94-92-90-88-86-84-82-80-78-76-74-72-67-41-38-54-48(57)37-40-56-49(58)35-36-50(56)59;43*1-2;/h35-36,38,41,47H,3-34,37,39-40,42-46H2,1-2H3,(H,54,57)(H,55,62)(H,63,64);43*1-2H2;1H3/b41-38-;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/t47-;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/m1............................................/s1 |
| InChI Key | BNRYDZYRCFCPTI-TVQPSUCNSA-N |
※ Please be kindly noted products are not for therapeutic use. We do not sell to patients.
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