DOTMA

Catalog NumberBL-M000099
CAS Number104872-42-6
DescriptionDOTMA is one of the first cationic lipid used for gene transfection. DOTMA carries a positive charge on the surface of liposomes which condenses anionic nucleic acids and promotes efficient interactions between the cell membrane and the liposome.
IUPAC Name2,3-bis[(Z)-octadec-9-enoxy]propyl-trimethylazanium;chloride
Synonyms1,2-Di-O-Octadecenyl-3-Trimethylammonium Propane; Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride; N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium
Molecular Weight670.57
Molecular FormulaC42H84ClNO2
Melting Point35-38 °C
Purity>98%
AppearanceWhite Powder
StorageStore at -20°C
Canonical SMILESCCCCCCCCC=CCCCCCCCCOCC(C[N+](C)(C)C)OCCCCCCCCC=CCCCCCCCC.[Cl-]
InChIInChI=1S/C42H84NO2.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-44-41-42(40-43(3,4)5)45-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h20-23,42H,6-19,24-41H2,1-5H3;1H/q+1;/p-1/b22-20-,23-21-;
InChI KeyLDGWQMRUWMSZIU-LQDDAWAPSA-M

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