DOPE
| Catalog Number | BL-M000051 |
| CAS Number | 4004-05-1 |
| Description | DOPE, also known as 1,2-Dioleoyl-sn-glycero-3-PE or 1,2-DOPE, is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. 1,2-DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery. |
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| IUPAC Name | [(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-[(Z)-octadec-9-enoyl]oxypropyl] (Z)-octadec-9-enoate |
| Synonyms | 18:1 PE; 1,2-Dioleoyl-sn-glycero-3-PE; 1,2-Dioleoyl-sn-glycero-3-Phosphoethanolamine; 1,2-DOPE |
| Molecular Weight | 744.1 |
| Molecular Formula | C41H78NO8P |
| Boiling Point | 759.22°C at 760 mmHg |
| Melting Point | 200 °C |
| Purity | 0.95 |
| Density | 1.008±0.06 g/cm3 (Predicted) |
| Solubility | Chloroform: 3.3 mg/ml |
| Appearance | Freeze-dried Powder |
| Shelf Life | ≥ 2 years |
| Storage | -20°C |
| Shipping | Ambient temperature |
| Lipid Number | PE(18:1(9Z)/18:1(9Z)) |
| Canonical SMILES | CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)OCCN)OC(=O)CCCCCCCC=CCCCCCCCC |
| InChI | InChI=1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)/b19-17-,20-18-/t39-/m1/s1 |
| InChI Key | MWRBNPKJOOWZPW-NYVOMTAGSA-N |
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