DLin-KC2-DMA

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Catalog Number Size Price Stock Quantity
BL-M000110 10 mg $298 In stock
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Catalog NumberBL-M000110
CAS Number1190197-97-7
DescriptionDLin-KC2-DMA is a cationic/ionizable lipid for siRNA delivery. DLin-KC2-DMA was formulated and characterized in SNALP and demonstrated to have in vivo activity at siRNA doses as low as 0.01 mg/kg in rodents and 0.1 mg/kg in nonhuman primates.
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IUPAC Name2-[2,2-bis[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine
Synonyms2,2-Dilinoleyl-4-dimethylaminoethyl-[1,3]-dioxolane; N,N-Dimethyl-2,2-di-(9Z,12Z)-9,12-octadecadien-1-yl-1,3-dioxolane-4-ethanamine; 2,2-Dilinoleyl-4-(2-dimethylaminoethyl)-1,3-dioxolane; 2-[2,2-Di-(9Z,12Z)-octadeca-9,12-dienyl-1,3-dioxolan-4-yl]-N,N-dimethylethanamine; DLin-K-XTC2-DMA; Dlin-KC2-DMA; D-Lin-KC2-DMA; XTC; XTC (synthetic lipid)
Molecular Weight642.09
Molecular FormulaC43H79NO2
Boiling Point668.1±40.0 °C at 760 mmHg
Purity>98%
Density0.885±0.06 g/cm3
SolubilitySoluble in Ethanol, DMSO, DMF
AppearanceColorless to light yellow liquid
StorageStore at -20 °C
Canonical SMILESCCCCCC=CCC=CCCCCCCCCC1(OCC(O1)CCN(C)C)CCCCCCCCC=CCC=CCCCCC
InChIInChI=1S/C43H79NO2/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-38-43(45-41-42(46-43)37-40-44(3)4)39-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h13-16,19-22,42H,5-12,17-18,23-41H2,1-4H3/b15-13-,16-14-,21-19-,22-20-
InChI KeyLRFJOIPOPUJUMI-KWXKLSQISA-N

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