cKK-E12

Catalog NumberBL-M001380
CAS Number1432494-65-9
DescriptioncKK-E12 is an ionizable lipid which is used to deliver RNA-based therapeutics. cKK-E12 has been used to deliver siRNA in mice, rats, and primates (ED50 = 0.002, 0.01, & 0.3 mg/kg respectively).
IUPAC Name3,6-bis[4-[bis(2-hydroxydodecyl)amino]butyl]piperazine-2,5-dione
Molecular Weight993.64
Molecular FormulaC60H120N4O6
Purity>95%
StorageStore at -20°C
Canonical SMILESCCCCCCCCCCC(CN(CCCCC1C(=O)NC(C(=O)N1)CCCCN(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O)O
InChIInChI=1S/C60H120N4O6/c1-5-9-13-17-21-25-29-33-41-53(65)49-63(50-54(66)42-34-30-26-22-18-14-10-6-2)47-39-37-45-57-59(69)62-58(60(70)61-57)46-38-40-48-64(51-55(67)43-35-31-27-23-19-15-11-7-3)52-56(68)44-36-32-28-24-20-16-12-8-4/h53-58,65-68H,5-52H2,1-4H3,(H,61,70)(H,62,69)
InChI KeyZISVTYVLWSZJAL-UHFFFAOYSA-N

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