C8 Ceramide

Catalog NumberBL-M001042
CAS Number74713-59-0
DescriptionA lipid molecule, C8 Ceramide is intricately involved in cell signaling pathways. Research has extensively explored its therapeutic potential in cancer treatment and neurodegenerative disorders. C8 Ceramide has demonstrated efficacy in triggering apoptosis in malignant cells and enhancing neuronal viability in neurodegenerative ailments.
IUPAC NameN-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]octanamide
SynonymsC8 Ceramide (d18:1/8:0); N-octanoyl-D-erythro-sphingosine; N-(octanoyl)-sphing-4-enine; N-octanoylsphingosine
Molecular Weight425.69
Molecular FormulaC26H51NO3
Boiling Point541.37°C at 760 mmHg
Melting Point68-70°C
Purity>99%
Density0.9974 g/cm3
SolubilitySoluble in DMSO (25 mg/ml), methanol, DMF (~20 mg/ml), and 100% ethanol (25 mg/ml).
AppearanceOff White Powder
ApplicationA biologically active, cell permeable, but nonphysiologic ceramide analog. It induces phosphorylation on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase. It stimulates IL-2 secretion and induces apoptosis.
Shelf Life1 Year
StorageStore at -20°C
Percent CompositionC 73.36%, H 12.08%, N 3.29%, O 11.28%
Canonical SMILESCCCCCCCCCCCCCC=CC(C(CO)NC(=O)CCCCCCC)O
InChIInChI=1S/C26H51NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h19,21,24-25,28-29H,3-18,20,22-23H2,1-2H3,(H,27,30)/b21-19+/t24-,25+/m0/s1
InChI KeyAPDLCSPGWPLYEQ-WRBRXSDHSA-N

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