C8 Ceramide
| Catalog Number | BL-M001042 |
| CAS Number | 74713-59-0 |
| Description | A lipid molecule, C8 Ceramide is intricately involved in cell signaling pathways. Research has extensively explored its therapeutic potential in cancer treatment and neurodegenerative disorders. C8 Ceramide has demonstrated efficacy in triggering apoptosis in malignant cells and enhancing neuronal viability in neurodegenerative ailments. |
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| IUPAC Name | N-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]octanamide |
| Synonyms | C8 Ceramide (d18:1/8:0); N-octanoyl-D-erythro-sphingosine; N-(octanoyl)-sphing-4-enine; N-octanoylsphingosine |
| Molecular Weight | 425.69 |
| Molecular Formula | C26H51NO3 |
| Boiling Point | 541.37°C at 760 mmHg |
| Melting Point | 68-70°C |
| Purity | >99% |
| Density | 0.9974 g/cm3 |
| Solubility | Soluble in DMSO (25 mg/ml), methanol, DMF (~20 mg/ml), and 100% ethanol (25 mg/ml). |
| Appearance | Off White Powder |
| Application | A biologically active, cell permeable, but nonphysiologic ceramide analog. It induces phosphorylation on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase. It stimulates IL-2 secretion and induces apoptosis. |
| Shelf Life | 1 Year |
| Storage | Store at -20°C |
| Percent Composition | C 73.36%, H 12.08%, N 3.29%, O 11.28% |
| Canonical SMILES | CCCCCCCCCCCCCC=CC(C(CO)NC(=O)CCCCCCC)O |
| InChI | InChI=1S/C26H51NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h19,21,24-25,28-29H,3-18,20,22-23H2,1-2H3,(H,27,30)/b21-19+/t24-,25+/m0/s1 |
| InChI Key | APDLCSPGWPLYEQ-WRBRXSDHSA-N |
※ Please be kindly noted products are not for therapeutic use. We do not sell to patients.
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