C6-ceramide
| Catalog Number | BL-M000948 |
| CAS Number | 124753-97-5 |
| Description | C6-ceramide, a sphingolipid molecule, plays a pivotal role in prompting apoptotic cell death and controlling intricate cellular mechanisms. Extensive research has explored its promising therapeutic prospects in combatting cancer, neurodegeneration, and inflammatory disorders. |
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| IUPAC Name | N-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]hexanamide |
| Synonyms | N-hexanoyl-D-erythro-sphingosine; C6 Ceramide (d18:1/6:0); N-hexanoylsphingosine |
| Molecular Weight | 397.63 |
| Molecular Formula | C24H47NO3 |
| Boiling Point | 574.7°C at 760 mmHg |
| Melting Point | 76-77°C |
| Flash Point | 301.4°C |
| Purity | >98% |
| Density | 0.946 g/cm3 |
| Solubility | water, 0.001415 mg/L @ 25 °C (est) |
| Appearance | Off White Powder |
| Application | A biologically active, cell permeable, but nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10 nM and activiates MAP kinase. It induces apoptosis and inhibits glycoproptein traffic by the secretory pathway |
| Shelf Life | 1 Year |
| Storage | Store at -20°C |
| Percent Composition | C 72.49%, H 11.91%, N 3.52%, O 12.07% |
| Canonical SMILES | CCCCCCCCCCCCCC=CC(C(CO)NC(=O)CCCCC)O |
| InChI | InChI=1S/C24H47NO3/c1-3-5-7-8-9-10-11-12-13-14-15-16-18-19-23(27)22(21-26)25-24(28)20-17-6-4-2/h18-19,22-23,26-27H,3-17,20-21H2,1-2H3,(H,25,28)/b19-18+/t22-,23+/m0/s1 |
| InChI Key | NPRJSFWNFTXXQC-QFWQFVLDSA-N |
※ Please be kindly noted products are not for therapeutic use. We do not sell to patients.
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