C6-ceramide

Catalog NumberBL-M000948
CAS Number124753-97-5
DescriptionC6-ceramide, a sphingolipid molecule, plays a pivotal role in prompting apoptotic cell death and controlling intricate cellular mechanisms. Extensive research has explored its promising therapeutic prospects in combatting cancer, neurodegeneration, and inflammatory disorders.
IUPAC NameN-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]hexanamide
SynonymsN-hexanoyl-D-erythro-sphingosine; C6 Ceramide (d18:1/6:0); N-hexanoylsphingosine
Molecular Weight397.63
Molecular FormulaC24H47NO3
Boiling Point574.7ºC at 760 mmHg
Melting Point76-77ºC
Flash Point301.4°C
Purity>98%
Density0.946 g/cm3
Solubilitywater, 0.001415 mg/L @ 25 °C (est)
AppearanceOff White Powder
ApplicationA biologically active, cell permeable, but nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10 nM and activiates MAP kinase. It induces apoptosis and inhibits glycoproptein traffic by the secretory pathway
Shelf Life1 Year
StorageStore at -20°C
Percent CompositionC 72.49%, H 11.91%, N 3.52%, O 12.07%
Canonical SMILESCCCCCCCCCCCCCC=CC(C(CO)NC(=O)CCCCC)O
InChIInChI=1S/C24H47NO3/c1-3-5-7-8-9-10-11-12-13-14-15-16-18-19-23(27)22(21-26)25-24(28)20-17-6-4-2/h18-19,22-23,26-27H,3-17,20-21H2,1-2H3,(H,25,28)/b19-18+/t22-,23+/m0/s1
InChI KeyNPRJSFWNFTXXQC-QFWQFVLDSA-N

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