C2 Adamantanyl Galactosylceramide (d18:1/2:0)
| Catalog Number | BL-M001087 |
| CAS Number | 574738-16-2 |
| Description | C2 Adamantanyl Galactosylceramide (d18:1/2:0) is a bioactive sphingolipid. It reduces globotriaosylceramide 3 synthesis from exogenous lactosylceramide in microsomes. AdaGalCer stimulates recombinant glucocerebrosidase activity in a pH-dependent manner. It activates glucocerebrosidase to decrease glucosylceramide accumulation in fibroblasts and lymphoblasts isolated from patients with Gaucher and Fabry disease, respectively. |
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| IUPAC Name | 2-(1-adamantyl)-N-[(E,2S,3R)-3-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadec-4-en-2-yl]acetamide |
| Synonyms | [(2S,3R,4E)-2-[(1-Adamantyl)acetylamino]-3-hydroxy-4-octadecenyl]beta-D-galactopyranoside; N-(1-Adamantaneacetyl)-galactosylceramide; Adamantanyl Galactosyl(β) Ceramide; AdaGalCer(d18:1/2:0) |
| Molecular Weight | 637.89 |
| Molecular Formula | C36H63NO8 |
| Purity | ≥98% |
| Solubility | Soluble in DMSO. |
| Appearance | Solid Powder |
| Shelf Life | 1 Year |
| Storage | Store at -20°C |
| Percent Composition | C 67.78%, H 9.95%, N 2.20%, O 20.07% |
| Canonical SMILES | CCCCCCCCCCCCCC=CC(C(COC1C(C(C(C(O1)CO)O)O)O)NC(=O)CC23CC4CC(C2)CC(C4)C3)O |
| InChI | InChI=1S/C36H63NO8/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-29(39)28(24-44-35-34(43)33(42)32(41)30(23-38)45-35)37-31(40)22-36-19-25-16-26(20-36)18-27(17-25)21-36/h14-15,25-30,32-35,38-39,41-43H,2-13,16-24H2,1H3,(H,37,40)/b15-14+/t25?,26?,27?,28-,29+,30+,32-,33-,34+,35+,36?/m0/s1 |
| InChI Key | JJKSFVGDPSOVJH-YAHKHYCISA-N |
※ Please be kindly noted products are not for therapeutic use. We do not sell to patients.
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