C16 Dihydroceramide (d18:0/16:0)
| Catalog Number | BL-M000946 |
| CAS Number | 5966-29-0 |
| Description | C16 Dihydroceramide is a dihydroceramide compound relevant to the study of ceramide synthase activity and sphingolipid generation. C16 Dihydroceramide (0-46 nM) inhibits C16 ceramide-induced membrane permeabilization, measured as cytochrome c oxidation, in rat liver mitochondria in a concentration-dependent manner. It also inhibits C16 ceramide-induced channel formation in liposomes. C16 Dihydroceramide is biologically inactive as a single agent, lacking the ability to induce apoptosis, cytochrome c release, or channel formation in phospholipid membranes in the absence of C16 ceramide. |
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| IUPAC Name | N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]hexadecanamide |
| Synonyms | N-(hexadecanoyl)-sphinganine; N-palmitoyl-D-erythro-sphinganine; N-16:0 Sphinganine; C16 Sphinganine; C16 dihydrosphingosine; Cer(d18:0/16:0) |
| Molecular Weight | 539.92 |
| Molecular Formula | C34H69NO3 |
| Boiling Point | 675.65°C at 760 mmHg |
| Melting Point | 100-102°C (lit.) |
| Purity | >99% |
| Density | 0.91 g/cm3 |
| Solubility | Soluble in Chloroform |
| Appearance | White Solid |
| Shelf Life | 1 Year |
| Storage | Store at -20°C |
| Percent Composition | C 75.63%, H 12.88%, N 2.59%, O 8.89% |
| Canonical SMILES | CCCCCCCCCCCCCCCC(C(CO)NC(=O)CCCCCCCCCCCCCCC)O |
| InChI | InChI=1S/C34H69NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(37)32(31-36)35-34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h32-33,36-37H,3-31H2,1-2H3,(H,35,38)/t32-,33+/m0/s1 |
| InChI Key | GCGTXOVNNFGTPQ-JHOUSYSJSA-N |
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