C16 Ceramide
| Catalog Number | BL-M000999 |
| CAS Number | 24696-26-2 |
| Description | C16 ceramide is an endogenous ceramide, generated by ceramide synthase 6 (CerS6), that acts as a lipid second messenger to regulate apoptosis and stress signaling. It has also been found to activate NF-κB and PKCζ3. |
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| IUPAC Name | N-(1,3-dihydroxyoctadec-4-en-2-yl)hexadecanamide |
| Synonyms | C16 Ceramide (d18:1/16:0); N-(hexadecanoyl)-sphing-4-enine |
| Molecular Weight | 537.90 |
| Molecular Formula | C34H67NO3 |
| Boiling Point | 675.4°C at 760 mmHg |
| Melting Point | 98-99°C |
| Purity | >99% |
| Density | 0.92 g/cm3 |
| Solubility | Soluble in ethanol (5 mg/ml, warm), DMF (~0.15 mg/ml), and Chloroform. Insoluble in water. |
| Appearance | White Crystalline Solid |
| Application | A predominant, rather hydrophobic natural ceramide. Activates a cytosolic serine/threonine protein phosphatase in T9 cells; induces EGF receptor phosphorylation in A-431 cells; stimulates ceramide-activated protein kinase. |
| Shelf Life | 1 Year |
| Storage | Store at -20°C |
| Percent Composition | C 75.92%, H 12.55%, N 2.60%, O 8.92% |
| Canonical SMILES | CCCCCCCCCCCCCCCC(=O)NC(CO)C(C=CCCCCCCCCCCCCC)O |
| InChI | InChI=1S/C34H67NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(37)32(31-36)35-34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,32-33,36-37H,3-26,28,30-31H2,1-2H3,(H,35,38) |
| InChI Key | YDNKGFDKKRUKPY-UHFFFAOYSA-N |
※ Please be kindly noted products are not for therapeutic use. We do not sell to patients.
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