C16 Ceramide

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Catalog Number Size Price Stock Quantity
BL-M000999 100 mg $899 In stock
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Catalog NumberBL-M000999
CAS Number24696-26-2
DescriptionC16 ceramide is an endogenous ceramide, generated by ceramide synthase 6 (CerS6), that acts as a lipid second messenger to regulate apoptosis and stress signaling. It has also been found to activate NF-κB and PKCζ3.
IUPAC NameN-(1,3-dihydroxyoctadec-4-en-2-yl)hexadecanamide
SynonymsC16 Ceramide (d18:1/16:0); N-(hexadecanoyl)-sphing-4-enine; N-Palmitoylsphingosine
Molecular Weight537.90
Molecular FormulaC34H67NO3
Boiling Point675.4°C at 760 mmHg
Melting Point98-99°C
Purity98%
Density0.92 g/cm3
SolubilitySoluble in ethanol (5 mg/ml, warm), DMF (~0.15 mg/ml), and Chloroform. Insoluble in water.
AppearanceWhite Crystalline Solid
ApplicationA predominant, rather hydrophobic natural ceramide. Activates a cytosolic serine/threonine protein phosphatase in T9 cells; induces EGF receptor phosphorylation in A-431 cells; stimulates ceramide-activated protein kinase.
Shelf Life1 Year
StorageStore at -20°C
Percent CompositionC 75.92%, H 12.55%, N 2.60%, O 8.92%
Canonical SMILESCCCCCCCCCCCCCCCC(=O)NC(CO)C(C=CCCCCCCCCCCCCC)O
InChIInChI=1S/C34H67NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(37)32(31-36)35-34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,32-33,36-37H,3-26,28,30-31H2,1-2H3,(H,35,38)
InChI KeyYDNKGFDKKRUKPY-UHFFFAOYSA-N

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