C16-20:4 PC

Catalog NumberBL-M000879
CAS Number86288-11-1
DescriptionC16-20:4 PC is the product of acylation of lyso-PAF C-16 by a CoA-independent transacylase. It is the most common precursor for formation of PAF C-16 by the remodeling pathway. Platelet-activating factor (PAF) is a pro-inflammatory lipid mediator that activates many cell types including leukocytes, platelets and vascular endothelial cells in response to cutaneous inflammation.
IUPAC Name[(2R)-3-hexadecoxy-2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
Synonyms1-O-hexadecyl-2-arachidonoyl-sn-glycero-3-phosphocholine; 1-O-hexadecyl-2-eicosatetraenoyl-sn-glycero-3-phosphocholine; PC(16:0e/20:4(5Z,8Z,11Z,14Z)); C16:0-20:4 PAF; 1-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine; Arachidonoyl PAF C-16
Molecular Weight768.10
Molecular FormulaC44H82NO7P
Purity>99%
SolubilitySoluble in DMSO (~2 mg/ml), DMF (~2 mg/ml), water (<0.05 mg/ml at 25°C), ethanol, and PBS (pH 7.2).
AppearanceOil dissolved in ethanol
Shelf Life3 Months
StorageStore at -20°C
Percent CompositionC 68.80%, H 10.76%, N 1.82%, O 14.58%, P 4.03%
Canonical SMILESCCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCC=CCC=CCC=CCC=CCCCCC
InChIInChI=1S/C44H82NO7P/c1-6-8-10-12-14-16-18-20-22-23-24-25-27-29-31-33-35-37-44(46)52-43(42-51-53(47,48)50-40-38-45(3,4)5)41-49-39-36-34-32-30-28-26-21-19-17-15-13-11-9-7-2/h14,16,20,22,24-25,29,31,43H,6-13,15,17-19,21,23,26-28,30,32-42H2,1-5H3/b16-14-,22-20-,25-24-,31-29-/t43-/m1/s1
InChI KeyDUUSFCFZBREELS-WWBBCYQPSA-N

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