Brain PI(4,5)P2 (ammonium salt)

Catalog NumberBL-M000745
CAS Number383907-42-4
DescriptionPIP2 is a component of membrane-bound receptors associated with PLC (phospholipase C). PIP2 is an activator of PKC (protein kinase C) in the presence of calcium ions phosphatidylserine. It potently stimulates brain PLD (phospholipase D) activity in vitro.
IUPAC Nametriazanium;[(2S,4R)-2,3,5-trihydroxy-6-[hydroxy(oxido)phosphoryl]oxy-4-[[(2R)-2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]oxy-3-octadecanoyloxypropoxy]-oxidophosphoryl]oxycyclohexyl] hydrogen phosphate
SynonymsL-α-phosphatidylinositol-4,5-bisphosphate (Brain, Porcine) (ammonium salt); 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-myo-inositol-4',5'-bisphosphate) (ammonium salt)
Molecular Weight1098.18
Molecular FormulaC47H94N3O19P3
Purity>99%
SolubilitySoluble in chloroform (50 mg/ml), and water (10 mg/ml).
AppearanceWhite to Off-white Solid
Shelf Life3 Months
StorageStore at -20°C
Canonical SMILESCCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OC1C(C(C(C(C1O)OP(=O)(O)[O-])OP(=O)(O)[O-])O)O)OC(=O)CCCC=CCC=CCC=CCC=CCCCCC.[NH4+].[NH4+].[NH4+]
InChIInChI=1S/C47H85O19P3.3H3N/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(49)63-39(37-61-40(48)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2)38-62-69(59,60)66-45-42(50)43(51)46(64-67(53,54)55)47(44(45)52)65-68(56,57)58;;;/h11,13,17,19,22,24,28,30,39,42-47,50-52H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3,(H,59,60)(H2,53,54,55)(H2,56,57,58);3*1H3/b13-11-,19-17-,24-22-,30-28-;;;/t39-,42?,43+,44?,45-,46?,47?;;;/m1.../s1
InChI KeyGAIOWTITBYPFJE-JVILRMJCSA-N

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