Azelaoyl PAF

Catalog NumberBL-M000342
CAS Number354583-69-0
DescriptionAzelaoyl-PAF is an alkyl phosphatidylcholine and is a component of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles, which contain low molecular weight species. It is a potent PPARγ agonist which competes for the thiazolidinedione binding site.
IUPAC Name[(2R)-2-(8-carboxyoctanoyloxy)-3-hexadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
Synonyms1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine; C16-09:0 (COOH) PC; 1-O-hexadecyl-2-nonadioyl-sn-glycero-3-phosphocholine; 1-O-Hexadecyl-2-O-(9-carboxyoctanoyl)-sn-glyceryl-3-phosphocholine
Molecular Weight651.85
Molecular FormulaC33H66NO9P
Boiling Point78-80°C at 760 mmHg
Melting Point-144°C
Purity>99%
SolubilitySoluble to 8 mg/ml in DMSO, to 33 mg/ml in DMF, and to 10 mg/ml in PBS (pH 7.2).
AppearanceChloroform
Shelf Life1 Year
StorageStore at -20°C
Percent CompositionC 60.80%, H 10.21%, N 2.15%, O 22.09%, P 4.75%
Canonical SMILESCCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC(=O)O
InChIInChI=1S/C33H66NO9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-20-23-27-40-29-31(30-42-44(38,39)41-28-26-34(2,3)4)43-33(37)25-22-19-17-18-21-24-32(35)36/h31H,5-30H2,1-4H3,(H-,35,36,38,39)/t31-/m1/s1
InChI KeyZDFOCDTXDPKJKA-WJOKGBTCSA-N

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