Arachidonic Acid-[d11]

Catalog NumberBL-M000561
CAS Number1287387-84-1
DescriptionLabelled Arachidonic acid. Arachidonic acid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules.
IUPAC Name(5Z,8Z,11Z,14Z)-16,16,17,17,18,18,19,19,20,20,20-undecadeuterioicosa-5,8,11,14-tetraenoic acid
Synonyms(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic Acid-d11; (all-Z)-5,8,11,14-Eicosatetraenoic Acid-d11; 5,8,11,14-all-cis-Eicosatetraenoicmmunocytophyte-d11; Immunocytophyte-d11; all-cis-5,8,11,14-Eicosatetraenoic Acid-d11; cis-5,8,11,14-Eicosatetraenoic Acid-d11
Molecular Weight315.53
Molecular FormulaC20H21D11O2
Boiling Point407.5±0.0 °C at 760 mmHg
Purity98% by CP; 98% atom D
Density0.9±0.1 g/cm3
AppearanceEthanol
Shelf Life3 months
StorageStore at -20°C
Percent CompositionC 76.13%, H 13.73%, O 10.14%
Canonical SMILESCCCCCC=CCC=CCC=CCC=CCCCC(=O)O
InChIInChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-/i1D3,2D2,3D2,4D2,5D2
InChI KeyYZXBAPSDXZZRGB-MBZQHBQHSA-N

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