15(R)-Prostaglandin F2α

Catalog NumberBL-M000688
CAS Number37658-84-7
Description15(R)-PGF2α is the C-15 epimer of the naturally occurring mammalian autacoid PGF2α. It has only 25% of the potency of PGF2α in hamster antifertility studies, which may be due to reduced affinity for FP receptors.
IUPAC Name(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid
Synonyms15-beta PGF2α; Prostaglandin F2α (15 beta epimer); 15-epi-PGF2alpha; 15R-Prostaglandin F2alpha
Molecular Weight354.49
Molecular FormulaC20H34O5
Purity>99%
SolubilitySoluble in water (10 mg/ml at 25° C), PBS pH 7.2 (~10 mg/ml), DMF ( ~ 100 mg/ml), DMSO (~100 mg/ml), and ethanol (~100 mg/ml).
AppearanceEthanol
Shelf Life1 Year
StorageStore at -20°C
Percent CompositionC 67.77%, H 9.67%, O 22.57%
Canonical SMILESCCCCCC(C=CC1C(CC(C1CC=CCCCC(=O)O)O)O)O
InChIInChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16-,17-,18+,19-/m1/s1
InChI KeyPXGPLTODNUVGFL-CKXCCYAOSA-N

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