15-Keto-PGF2alpha
| Catalog Number | BL-M000691 |
| CAS Number | 35850-13-6 |
| Description | 15-Keto-PGF2alpha is the first metabolite of PGF2α, biosynthesized by 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH). 15-Keto-PGF2alpha is reportedly 10-folds less active than PGF2α at decreasing rabbit intraocular pressure. |
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| IUPAC Name | (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxooct-1-enyl]cyclopentyl]hept-5-enoic acid |
| Synonyms | 5β-cholanic acid-3α,12α-diol N-(carboxymethyl)-amide; 15-Ketoprostaglandin F2alpha; 15-oxo-prostaglandin F2alpha; 9S,11R-dihydroxy-15-oxo-5Z,13E-prostadienoic acid |
| Molecular Weight | 352.47 |
| Molecular Formula | C20H32O5 |
| Purity | >99% |
| Density | 1.149 g/cm3 |
| Solubility | Soluble in ethanol, water (10 mg/ml) at 25 °C, PBS pH 7.2, DMF, and DMSO. |
| Appearance | Solution in methyl acetate |
| Shelf Life | 1 Year |
| Storage | Store at -20°C |
| Percent Composition | C 68.15%, H 9.15%, O 22.70% |
| Canonical SMILES | CCCCCC(=O)C=CC1C(CC(C1CC=CCCCC(=O)O)O)O |
| InChI | InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,16-19,22-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t16-,17-,18+,19-/m1/s1 |
| InChI Key | LOLJEILMPWPILA-AMFHKTBMSA-N |
※ Please be kindly noted products are not for therapeutic use. We do not sell to patients.
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