1,2-Dioctanoyl-sn-glycerol

Catalog NumberBL-M000649
CAS Number60514-48-9
Description1,2-Dioctanoyl-sn-glycerol is a cell-permeable activator of protein kinase C (PKC). 1,2-Dioctanoyl-sn-glycerol shows lower affinity for PKCa than for other isozymes. It is shown to mimic the effects of tumor-promoting phorbol diesters on mitogenesis and epidermal growth factor binding and action in intact cells.
IUPAC Name[(2S)-3-hydroxy-2-octanoyloxypropyl] octanoate
SynonymsOctanoic acid, 1,1'-[(1S)-1-(hydroxymethyl)-1,2-ethanediyl] ester; Octanoic acid, (1S)-1-(hydroxymethyl)-1,2-ethanediyl ester; Octanoic acid, 1-(hydroxymethyl)-1,2-ethanediyl ester, (S)-; (S)-3-Hydroxypropane-1,2-diyl dioctanoate; DiC 8; sn-1,2-Dioctanoylglycerol
Molecular Weight344.49
Molecular FormulaC19H36O5
Boiling Point429.1±12.0°C at 760 mmHg
Melting Point81-82°C
Purity>99%
Density0.992±0.06 g/cm3
SolubilitySoluble in DMSO (7 mg/ml), chloroform, 100% ethanol, dichloromethane, ether, ethyl acetate, methanol, most organic solvents, DMF (7 mg/ml), PBS (pH 7.2) (250 ug/ml), water (>250 ug/ml at 25°C), and cyclohexane.
AppearanceColourless to Pale Yellow Oil to Low-melting Solid
Shelf Life1 Year
StorageStore at -20°C
Percent CompositionC 66.25%, H 10.53%, O 23.22%
Canonical SMILESCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCC
InChIInChI=1S/C19H36O5/c1-3-5-7-9-11-13-18(21)23-16-17(15-20)24-19(22)14-12-10-8-6-4-2/h17,20H,3-16H2,1-2H3/t17-/m0/s1
InChI KeyZQBULZYTDGUSSK-KRWDZBQOSA-N

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